Cinobufaginol |
| رقم الكتالوجGC35697 |
Cinobufaginol هو بوفادينوليد طبيعي معزول من سم الضفدع الذي استخدم على نطاق واسع لعدة قرون في الصين لعلاج الأمراض المختلفة ، وخاصة السرطان. Cinobufaginol يثبط بقوة النشاط ضد خطوط خلايا سرطان البلعوم البشري مع IC50s 803 μ؛ μ؛ و 1.270 μ ؛ μ ؛ لـ CNE-1 و CNE-2Z ، على التوالي.
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Cas No.: 6691-83-4
Sample solution is provided at 25 µL, 10mM.
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Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μμ and 1.270 μμ for CNE-1 and CNE-2Z, respectively[1].
[1]. Liu JS, et al. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolidesfrom toad venom. Fitoterapia. 2019 Apr;134:362-371.
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