Cinobufaginol |
| カタログ番号GC35697 |
シノブファギノールはヒキガエルの毒から分離された天然のブファジエノライドで、中国では何世紀にもわたってさまざまな病気、特にがんの治療に広く使用されてきました。シノブファギノールは、803 μμ の IC50 で、ヒト鼻咽頭癌細胞株に対する活性を強力に阻害します。および 1.270 μμそれぞれ CNE-1 および CNE-2Z 用。
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Cas No.: 6691-83-4
Sample solution is provided at 25 µL, 10mM.
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Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μμ and 1.270 μμ for CNE-1 and CNE-2Z, respectively[1].
[1]. Liu JS, et al. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolidesfrom toad venom. Fitoterapia. 2019 Apr;134:362-371.
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