KPLH1130 |
| رقم الكتالوجGC36396 |
KPLH1130 هو مثبط محدد لإنزيم بيروفيت ديهيدروجينيز كيناز (PDK) ، ويمنع استقطاب البلاعم ويخفف من الاستجابات الالتهابية
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 906669-07-6
Sample solution is provided at 25 µL, 10mM.
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KPLH1130 is a specific pyruvate dehydrogenase kinase (PDK) inhibitor, blocks macrophage polarization and attenuates proinflammatory responses. KPLH1130 improves glucose tolerance in HFD-fed mice[1]. PDK[1]
[1]. Min BK, et al. Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype. Front Immunol. 2019 May 7;10:944.
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
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