C5a Inhibitory Sequence |
| رقم الكتالوجGA21237 |
The C5a-related octapeptide Phe-Lys-Ala-Cha-Cha-Leu-D-Ala-Arg possesses a high binding affinity for polymorphonuclear leukocyte membranes (Ki = 0.09 µM). It has therefore been used as a leading analog for the development of specific C5a antagonists, which are of considerable therapeutic interest for the treatment of inflammatory disorders and tissue damage.
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Cas No.: 133214-60-5
Sample solution is provided at 25 µL, 10mM.
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The C5a-related octapeptide Phe-Lys-Ala-Cha-Cha-Leu-D-Ala-Arg possesses a high binding affinity for polymorphonuclear leukocyte membranes (Ki = 0.09 µM). It has therefore been used as a leading analog for the development of specific C5a antagonists
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