C5a Inhibitory Sequence |
カタログ番号GA21237 |
C5a関連のオクタペプチドであるPhe-Lys-Ala-Cha-Cha-Leu-D-Ala-Argは、好中球膜に対して高い結合親和性を持っています(Ki = 0.09μM)。そのため、特定のC5a拮抗剤の開発のための先導アナログとして使用されており、炎症性障害や組織損傷の治療に非常に興味深いものです。
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Cas No.: 133214-60-5
Sample solution is provided at 25 µL, 10mM.
The C5a-related octapeptide Phe-Lys-Ala-Cha-Cha-Leu-D-Ala-Arg possesses a high binding affinity for polymorphonuclear leukocyte membranes (Ki = 0.09 µM). It has therefore been used as a leading analog for the development of specific C5a antagonists
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