Trifluoperazine N-Glucuronide (Synonyms: TFP N-Glucuronide) |
| رقم الكتالوجGC49217 |
يتم التعبير عن Trifluoperazine N-Glucuronide (UGT1A4) ، كأحد الأشكال الإسوية UGT1A البشرية ، في الكبد
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Cas No.: 165602-90-4
Sample solution is provided at 25 µL, 10mM.
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Trifluoperazine N-glucuronide is a metabolite of the antipsychotic agent trifluoperazine .1,2 It is formed from trifluoperazine by the UDP-glucuronosyltransferase (UGT) isoform UGT1A4.2
1.Luo, H., Hawes, E.M., McKay, G., et al.N(+)-glucuronidation of aliphatic tertiary amines in human: antidepressant versus antipsychotic drugsXenobiotica25(3)291-301(1995) 2.Fujiwara, R., Nakajima, M., Yamanaka, H., et al.Interactions between human UGT1A1, UGT1A4, and UGT1A6 affect their enzymatic activitiesDrug Metab. Dispos.35(10)1781-1787(2007)
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