CAY10684 |
رقم الكتالوجGC43191 |
Prostaglandin E2 activates four E prostanoid (EP) receptors, EP1-4.
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Cas No.: 493035-81-7
Sample solution is provided at 25 µL, 10mM.
Prostaglandin E2 activates four E prostanoid (EP) receptors, EP1-4. EP4 is a G protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10684 is a lactam that acts as a potent EP4 agonist, triggering cAMP signaling with an EC50 value of 0.8 nM. It displays more than 1,000-fold selectivity for EP4 over other EP receptors.
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