CPT-157633 |
| رقم الكتالوجGC62909 |
CPT-157633 ، أحد مشتقات ديفلورو- فوسفونوميثيل فينيل ألانين ، ومثبط PTP1B.
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Cas No.: 888213-72-7
Sample solution is provided at 25 µL, 10mM.
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CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance[1].
CPT-157633 (0.2 µg/day; intracerebroventricular infusion) alleviates the hypothalamic inflammation and glucose intolerance induced by binge drinking in rats[1].
[1]. Lindtner C, et, al. Binge drinking induces whole-body insulin resistance by impairing hypothalamic insulin action. Sci Transl Med. 2013 Jan 30;5(170):170ra14.
Average Rating: 5 (Based on Reviews and 16 reference(s) in Google Scholar.)
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