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CPT-157633

Katalog-Nr.GC62909

CPT-157633, ein Difluor-Phosphonomethyl-Phenylalanin-Derivat und ein PTP1B-Inhibitor.

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CPT-157633 Chemische Struktur

Cas No.: 888213-72-7

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5 mg
522,00 $
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10 mg
882,00 $
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25 mg
1.755,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance[1].

CPT-157633 (0.2 µg/day; intracerebroventricular infusion) alleviates the hypothalamic inflammation and glucose intolerance induced by binge drinking in rats[1].

[1]. Lindtner C, et, al. Binge drinking induces whole-body insulin resistance by impairing hypothalamic insulin action. Sci Transl Med. 2013 Jan 30;5(170):170ra14.

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