CZC-8004 (CZC-00008004) (Synonyms: Dianilinopyrimidine-01) |
| رقم الكتالوجGC33351 |
CZC-8004 (CZC-00008004) (CZC-00008004) ، أمينوبيريميدين ، هو مثبط بان-كينيز. يمكن لـ CZC-8004 (CZC-00008004) ربط مجموعة من كينازات التيروزين ، بما في ذلك EGFR و VEGFR2 بقيم IC50 البالغة 650 و 437 نانومتر ، على التوالي.
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Cas No.: 916603-07-1
Sample solution is provided at 25 µL, 10mM.
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CZC-8004 is a pan-kinase inhibitor and binds a range of tyrosine kinases, including ABL kinase.
[1]. CZC-8004 is a pan-kinase inhibitor, with low micromolar IC50 values for tyrosine kinase. [2]. Bantscheff M, et al. Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors. Nat Biotechnol. 2007 Sep;25(9):1035-44.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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