الصفحة الرئيسية>>Signaling Pathways>> Membrane Transporter/Ion Channel>> CFTR>>Dirocaftor

Dirocaftor

رقم الكتالوجGC64121

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Dirocaftor التركيب الكيميائي

Cas No.: 2137932-23-9

الحجم السعر المخزون الكميّة
5 mg
405٫00
متوفر
10 mg
720٫00
متوفر
25 mg
1485٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Dirocaftor (PTI-808) is a CFTR potentiator that enhances the function of CFTR protein by opening chloride channels. Dirocaftor can be used for cystic fibrosis (CF) research[1][2].

When combined with Nesolicaftor and Posenacaftor, Dirocaftor can restore CFTR function to nearly normal levels[2].

[1]. James A Reihill, et al. Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis. Genes (Basel). 2021 Mar 22;12(3):453.
[2]. P. van Mourik, et al. WS10 Moving beyond body mass index to assess nutritional status in CF. Journal of Cystic Fibrosis 19S2 (2020) S1-S36.

مراجعات

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Average Rating: 5 ★★★★★ (Based on Reviews and 7 reference(s) in Google Scholar.)

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