Dirocaftor |
Katalog-Nr.GC64121 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2137932-23-9
Sample solution is provided at 25 µL, 10mM.
Dirocaftor (PTI-808) is a CFTR potentiator that enhances the function of CFTR protein by opening chloride channels. Dirocaftor can be used for cystic fibrosis (CF) research[1][2].
When combined with Nesolicaftor and Posenacaftor, Dirocaftor can restore CFTR function to nearly normal levels[2].
[1]. James A Reihill, et al. Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis. Genes (Basel). 2021 Mar 22;12(3):453.
[2]. P. van Mourik, et al. WS10 Moving beyond body mass index to assess nutritional status in CF. Journal of Cystic Fibrosis 19S2 (2020) S1-S36.
Average Rating: 5
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