DMAPP (ammonium salt) (Synonyms: Dimethylallyl Pyrophosphate) |
| رقم الكتالوجGC43502 |
ثلاثي أمونيوم DMAPP (ثنائي ميثيل أليل بيروفوسفات) هو سلائف إيزوبرينويد.
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Cas No.: 1186-30-7
Sample solution is provided at 25 µL, 10mM.
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DMAPP (Dimethylallyl pyrophosphate) serves as a pivotal isoprenoid precursor within the realm of biogenic isoprenoid synthesis. It finds its origin as a metabolic product originating from two primary pathways: the mevalonate pathway and the MEP (2-C-methyl-D-erythritol 4-phosphate) pathway, both being prominent conduits for isoprenoid precursor biosynthesis in diverse biological systems. Remarkably, DMAPP stands as an isomeric counterpart to isopentenyl pyrophosphate (IPP), constituting a prevalent molecular entity that ubiquitously permeates the living kingdom[1-2].
References:
[1]. Mus AA, Goh LPW, Marbawi H, Gansau JA. The Biosynthesis and Medicinal Properties of Taraxerol. Biomedicines. 2022 Mar 30;10(4):807. doi: 10.3390/biomedicines10040807. PMID: 35453556; PMCID: PMC9025716.
[2]. Wang W, Oldfield E. Bioorganometallic chemistry with IspG and IspH: structure, function, and inhibition of the [Fe(4)S(4)] proteins involved in isoprenoid biosynthesis. Angew Chem Int Ed Engl. 2014 Apr 22;53(17):4294-310. doi: 10.1002/anie.201306712. Epub 2014 Jan 31. PMID: 24481599; PMCID: PMC3997630.
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