الصفحة الرئيسية>>Signaling Pathways>> Immunology/Inflammation>> Reactive Oxygen Species>>DMNQ

DMNQ (Synonyms: NSC 69355)

رقم الكتالوجGC40557 Copy One-Click Copy Product Info

DMNQ هو عامل تدوير الأكسدة والاختزال الذي يولد كل من الأكسيد الفائق وبيروكسيد الهيدروجين داخل الخلايا بطريقة تعتمد على التركيز

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DMNQ التركيب الكيميائي

Cas No.: 6956-96-3

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
79٫00
متوفر
1mg
33٫00
متوفر
5mg
120٫00
متوفر
10mg
214٫00
متوفر
25mg
416٫00
متوفر
50mg
337٫00
متوفر
100mg
491٫00
متوفر

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مراجعات العميل

بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of DMNQ

DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and hydrogen peroxide formation. The amount of oxidative stress is proportional to the amount of DMNQ applied and can alter diverse cellular parameters, including signal transduction, mitochondrial function, and gene expression.

Chemical Properties of DMNQ

Cas No. 6956-96-3 SDF
المرادفات NSC 69355
Canonical SMILES O=C1C(OC)=C(OC)C(C2=CC=CC=C21)=O
Formula C12H10O4 M.Wt 218.2
الذوبان DMSO: Soluble,Methanol: Soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of DMNQ

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.583 mL 22.9148 mL 45.8295 mL
5 mM 916.6 μL 4.583 mL 9.1659 mL
10 mM 458.3 μL 2.2915 mL 4.583 mL
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In vivo Formulation Calculator (Clear solution) of DMNQ

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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مراجعات

Review for DMNQ

Average Rating: 5 ★★★★★ (Based on Reviews and 21 reference(s) in Google Scholar.)

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