Dorzagliatin |
رقم الكتالوجGC39529 |
Dorzagliatin (HMS5552) ، منشط جلوكوكيناز ثنائي المفعول (GK) ، يحسن التحكم في نسبة السكر في الدم ووظيفة خلايا البنكرياس في مرض السكري من النوع 2
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Cas No.: 1191995-00-2
Sample solution is provided at 25 µL, 10mM.
Dorzagliatin (HMS5552), a dual-acting glucokinase (GK) activator, improves glycaemic control and pancreatic β-cell function in type 2 diabetes[1].
[1]. Zhu XX, et al. Dorzagliatin (HMS5552), a novel dual-acting glucokinase activator, improves glycaemic control and pancreatic β-cell function in patients with type 2 diabetes: A 28-day treatment study using biomarker-guided patient selection. Diabetes Obes Metab. 2018 Sep;20(9):2113-2120. [2]. Wang P, et al. Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus. J Diabetes Res. 2017;2017:5812607.
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