DP-C-4 |
| رقم الكتالوجGC62942 |
DP-C-4 هو PROTAC مزدوج قائم على Cereblon للتدهور المتزامن لـ EGFR و PARP
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1].
DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1].
[1]. Mengzhu Zheng, et al. Rational Design and Synthesis of Novel Dual PROTACs for Simultaneous Degradation of EGFR and PARP. J Med Chem. 2021 May 26.
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
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