(E/Z)-Sulindac sulfide |
| رقم الكتالوجGC67476 |
(E / Z) - كبريتيد السولينداك هو عامل قوي γ ؛ -مُعدِّل سريتاز (GSM). (E / Z) - يقلل كبريتيد السولينداك بشكل انتقائي من Aβ ؛ 42 إنتاج لصالح Aβ أقصر ؛ محيط. (E / Z) - يمكن استخدام كبريتيد السولينداك للبحث عن مرض الزهايمر.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 32004-67-4
Sample solution is provided at 25 µL, 10mM.
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(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM). (E/Z)-Sulindac sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer's disease[1].
[1]. Richter L, et al. Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602.
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