(E/Z)-Sulindac sulfide |
Catalog No.GC67476 |
(E/Z)-Sulindac sulfide는 강력한 γ-secretase modulator(GSM)입니다. 821d96072c2d58d8970e76f526b0f6b8(E/Z)-Sulindac sulfide는 Aβ을 선택적으로 감소시키고; 821d96072c2d58d8970e76f526b0f6b8종. (E/Z)-Sulindac sulfide는 알츠하이머병 연구에 사용할 수 있습니다.821d96072c2d58d8970e76f526b0f6b8
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Cas No.: 32004-67-4
Sample solution is provided at 25 µL, 10mM.
(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM). (E/Z)-Sulindac sulfide selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer's disease[1].
[1]. Richter L, et al. Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerization. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14597-602.
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