الصفحة الرئيسية>>Signaling Pathways>> Neuroscience>> COX>>Ethyl p-methoxycinnamate

Ethyl p-methoxycinnamate (Synonyms: EPMC, Ethyl 4-methoxycinnamate, Ethyl para-methoxycinnamate)

رقم الكتالوجGC43635

Ethyl p-methoxycinnamate هو منتج طبيعي موجود في Kaempferia galangal مع تأثيرات مضادة للالتهابات ومضادة للأورام ومضادة للميكروبات.

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Ethyl p-methoxycinnamate التركيب الكيميائي

Cas No.: 24393-56-4

الحجم السعر المخزون الكميّة
1g
42٫00
متوفر
5g
59٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Ethyl p-methoxycinnamate (EPMC) is a natural product found in K. galanga and C. zedoaria extracts with anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities. It inhibits COX-1 and COX-2 in vitro (IC50s = 1.12 and 0.83 μM, respectively) and reduces IL-1 and TNF-α production in vivo. EPMC inhibits granuloma tissue formation and acts as an analgesic, delaying tail flick time, in a dose-dependent manner in rats. It inhibits blood vessel growth in rat aortic explants (IC50 = 91.9 μg/ml). EPMC (T. rubrum, A. niger, S. cerevisiae, and E. floccosum and is larvicidal (LC50 = 53.64 ppm) against Ae. aegypti.

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