Etripamil (Synonyms: MSP-2017; (-)-MSP-2017) |
| رقم الكتالوجGC65248 |
Etripamil (MSP-2017) هو مضاد قصير المفعول لقناة الكالسيوم من النوع L ، ويمكن استخدامه في البحث عن عدم انتظام دقات القلب الانتيابي فوق البطيني (PSVT)
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Cas No.: 1593673-23-4
Sample solution is provided at 25 µL, 10mM.
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Etripamil (MSP-2017) is a short-acting L-type calcium-channel antagonist, can be used for the research of Paroxysmal Supraventricular Tachycardia (PSVT). Etripamil (MSP-2017) slows atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells[1][2].
[1]. Stambler BS, et al. Etripamil Nasal Spray for Rapid Conversion of Supraventricular Tachycardia to Sinus Rhythm. J Am Coll Cardiol. 2018 Jul 31;72(5):489-497.
[2]. Milestone Pharmaceuticals Announces USAN Approval of Generic Name "Etripamil" for its Phase 2 Clinical Development Product for the Treatment of Paroxysmal Supraventricular Tachycardia.
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