FIDAS-5 |
رقم الكتالوجGC39487 |
FIDAS-5 هو مثبط قوي وفعال عن طريق الفم ميثيونين S-adenosyltransferase 2A (MAT2A) مع IC 50 من 2.1 ميكرومتريتنافس FIDAS-5 بشكل فعال ضد S-adenosylmethionine (SAM) لربط MAT2Aيحتوي FIDAS-5 على أنشطة مضادة للسرطان
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Cas No.: 1391934-98-7
Sample solution is provided at 25 µL, 10mM.
FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 has anticancer activities[1].
[1]. Zhang W, et al. Fluorinated N,N-dialkylaminostilbenes repress colon cancer by targeting methionine S-adenosyltransferase 2A. ACS Chem Biol. 2013 Apr 19;8(4):796-803.
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