Fomepizole (Synonyms: 4-Methylpyrazole) |
| رقم الكتالوجGC17914 |
Fomepizole (4-Methylpyrazole) هو مثبط قوي للسيتوكروم P450 (CYP2E1)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 7554-65-6
Sample solution is provided at 25 µL, 10mM.
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Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase which plays a key role in the metabolism of ethylene glycol and methanol.
References:
[1]. Casavant MJ. Fomepizole in the treatment of poisoning. Pediatrics. 2001 Jan;107(1):170.
[2]. Lepik KJ, et al. Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole. Ann Emerg Med. 2009 Apr;53(4):439-450.e10.
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