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Auristatin E

رقم الكتالوجGC35429

Auristatin E هو معدّل لتوبيولين سام للخلايا مع نشاط مضاد للأورام قوي وانتقائي ؛ نظير MMAE والسم الخلوي في اتحادات الأجسام المضادة والأدويةيمنع Auristatin E انقسام الخلايا عن طريق منع بلمرة التوبولين

Products are for research use only. Not for human use. We do not sell to patients.

Auristatin E التركيب الكيميائي

Cas No.: 160800-57-7

الحجم السعر المخزون الكميّة
100mg
116٫00
متوفر
5mg
32٫00
متوفر
10mg
44٫00
متوفر
50mg
83٫00
متوفر
250mg
232٫00
متوفر
500mg
371٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

مراجعات العميل

بناء على آراء العملاء.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates.

[1]. Francisco JA, et al. cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity. Blood. 2003 Aug 15;102(4):1458-65. [2]. Li D, et al. DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma. Mol Cancer Ther. 2013 Jul;12(7):1255-65.

مراجعات

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Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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