C-11 |
| رقم الكتالوجGC35574 |
C-11 هو مثبط للتوبيولين ويعمل كسم خلوي ADC ، ويعرض السمية الخلوية لخطوط الخلايا السرطانية
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2007965-97-9
Sample solution is provided at 25 µL, 10mM.
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C-11 is a tubulysin-based drug-linker conjugate for ADC, displays cytotoxicity for carcinoma cell lines[1].
C-11 exhibits cytotoxicity for N87 cells and MDA-MB-361-DYT2 cells with IC50s of 1.11 nM and 0.9 nM, respectively[1].
[1]. Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7(11):999-1004.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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