C-11 |
Catalog No.GC35574 |
C-11은 튜불린 억제제이며 ADC 세포독소로 작용하여 암종 세포주에 대한 세포독성을 나타냅니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2007965-97-9
Sample solution is provided at 25 µL, 10mM.
C-11 is a tubulysin-based drug-linker conjugate for ADC, displays cytotoxicity for carcinoma cell lines[1].
C-11 exhibits cytotoxicity for N87 cells and MDA-MB-361-DYT2 cells with IC50s of 1.11 nM and 0.9 nM, respectively[1].
[1]. Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7(11):999-1004.
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