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Cetirizine D4 dihydrochloride

رقم الكتالوجGC35655 Copy One-Click Copy Product Info

السيتريزين D4 ثنائي هيدروكلوريد هو الديوتيريوم المسمى السيتريزين

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Cetirizine D4 dihydrochloride التركيب الكيميائي

الحجم السعر المخزون الكميّة
1mg
167٫00
متوفر
5mg
603٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com


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بناء على آراء العملاء.

Sample solution is provided at 25 µL, 10mM.



Description of Cetirizine D4 dihydrochloride

Cetirizine D4 2Hcl is deuterium labeled Cetirizine, which is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist.

Chemical Properties of Cetirizine D4 dihydrochloride

Cas No. SDF
Canonical SMILES ClC1=CC=C(C(N2CCN(C([2H])([2H])C([2H])([2H])OCC(O)=O)CC2)C3=CC=CC=C3)C=C1.Cl.Cl
Formula C21H23D4Cl3N2O3 M.Wt 465.83
الذوبان Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Cetirizine D4 dihydrochloride

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.1467 mL 10.7335 mL 21.4671 mL
5 mM 429.3 μL 2.1467 mL 4.2934 mL
10 mM 214.7 μL 1.0734 mL 2.1467 mL
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In vivo Formulation Calculator (Clear solution) of Cetirizine D4 dihydrochloride

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Review for Cetirizine D4 dihydrochloride

Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

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