Home>>Signaling Pathways>> Neuroscience>> Histamine Receptor>>Cetirizine D4 dihydrochloride

Cetirizine D4 dihydrochloride

Catalog No.GC35655 Copy One-Click Copy Product Info

Cetirizine D4 dihydrochloride is a deuterium labeled Cetirizine.

Products are for research use only. Not for human use. We do not sell to patients.

Cetirizine D4 dihydrochloride Chemical Structure

Size Price Stock Qty
1mg
$167.00
In stock
5mg
$603.00
In stock

Tel:(909) 407-4943 Email: sales@glpbio.com


Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Cetirizine D4 dihydrochloride

Cetirizine D4 2Hcl is deuterium labeled Cetirizine, which is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist.

Chemical Properties of Cetirizine D4 dihydrochloride

Cas No. SDF
Canonical SMILES ClC1=CC=C(C(N2CCN(C([2H])([2H])C([2H])([2H])OCC(O)=O)CC2)C3=CC=CC=C3)C=C1.Cl.Cl
Formula C21H23D4Cl3N2O3 M.Wt 465.83
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Cetirizine D4 dihydrochloride

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.1467 mL 10.7335 mL 21.4671 mL
5 mM 429.3 μL 2.1467 mL 4.2934 mL
10 mM 214.7 μL 1.0734 mL 2.1467 mL
  • Molarity Calculator

  • Dilution Calculator

  • Molecular Weight Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

Calculate

In vivo Formulation Calculator (Clear solution) of Cetirizine D4 dihydrochloride

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

View current batch:

Reviews

Review for Cetirizine D4 dihydrochloride

Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%