CGP 36742 (Synonyms: 3-Aminopropyl-n-butylphosphinic Acid, SGS 742) |
| رقم الكتالوجGC35669 |
CGP 36742 هو مضاد انتقائي لمستقبلات GABAB يمكنه اختراق الحاجز الدموي الدماغي بعد الإعطاء المحيطي ، مع IC 50 من 32 ميكرومتر
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Cas No.: 123690-78-8
Sample solution is provided at 25 µL, 10mM.
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CGP 36742 is a selective GABAB receptor antagonist that can penetrate the blood-brain barrier after peripheral administration, with an IC50 of 32 μM. CGP 36742 is useful in treatment of depression[1]. IC50: 32 μM (GABAB)[1]
[1]. Nowak G, et al. Antidepressant-like activity of CGP 36742 and CGP 51176, selective GABAB receptor antagonists, in rodents. Br J Pharmacol. 2006 Nov;149(5):581-90.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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