Dihydrexidine |
| رقم الكتالوجGC35864 |
ثنائي هيدروكسيدين (DAR-0100) هو ناهض عالي الفعالية وانتقائي وكامل لمستقبلات الدوبامين D1 (D1 / D5) مع IC50 من 10 نانومتر لمستقبل D1
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 123039-93-0
Sample solution is provided at 25 µL, 10mM.
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Dihydrexidine (DAR-100) is a high potent, selective and full efficacy D1 dopamine receptor agonist with an IC50 of 10 nM, and displays some affinity for the D2 receptor. Dihydrexidine (DAR-100) exhibits potent antiparkinsonian activity[1][2][3]. IC50: 10 nM (D1 dopamine receptor)[1]
[1]. Lovenberg TW, et al. Dihydrexidine, a novel selective high potency full dopamine D-1 receptor agonist. Eur J Pharmacol. 1989 Jul 4;166(1):111-3. [2]. Mottola DM, et al. Dihydrexidine, a novel full efficacy D1 dopamine receptor agonist. J Pharmacol Exp Ther. 1992 Jul;262(1):383-93. [3]. Salmi P,et al. Dihydrexidine--the first full dopamine D1 receptor agonist. CNS Drug Rev. 2004 Fall;10(3):230-42.
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