Exendin-3 |
رقم الكتالوجGC36019 |
Exendin-3 عبارة عن ببتيدات نشطة بيولوجيًا معزولة من سموم سحالي وحش Gila ، Heloderma horridurn
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 130357-25-4
Sample solution is provided at 25 µL, 10mM.
Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn . VIP receptor, putative exendin receptor[1]
Exendin-3 interacts with at least two receptors on guinea pig pancreatic acini; at high concentrations (>100 nM) the peptide interacts with VIP receptors, thereby causing a large increase in cAMP and stimulating amylase release; at lower concentrations (0.1-3 nM) the peptide interacts with a putative exendin receptor, thereby causing a smaller increase in cAMP of undetermined function[1].
[1]. Raufman JP, et al. Exendin-3, a novel peptide from Heloderma horridum venom, interacts with vasoactive intestinal peptide receptors and a newly described receptor on dispersed acini from guinea pig pancreas. Description of exendin-3(9-39) amide, a specific exendin receptor antagonist. J Biol Chem. 1991 Feb 15;266(5):2897-902.
Average Rating: 5
(Based on Reviews and 19 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *