FLT3-IN-6 |
| رقم الكتالوجGC36056 |
FLT3-IN-6 هو مثبط قوي وانتقائي لـ FLT3-ITD (طفرة FLT3) مع IC50 من 1.336 نانومتر
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Cas No.: 2377141-31-4
Sample solution is provided at 25 µL, 10mM.
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FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM[1]. IC50: 1.336 nM (FLT3-ITD)[1]
[1]. Heng H, et al. Combining structure- and property-based optimization to identify selective FLT3-ITD inhibitors with good antitumor efficacy in AML cell inoculated mouse xenograft model. Eur J Med Chem. 2019 Aug 15;176:248-267.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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