>>Signaling Pathways>> Tyrosine Kinase>> FLT3>>FLT3-IN-6

FLT3-IN-6

Catalog No.GC36056

FLT3-IN-6은 IC50이 1.336nM인 FLT3-ITD(FLT3 돌연변이)의 강력하고 선택적 억제제입니다.

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FLT3-IN-6 Chemical Structure

Cas No.: 2377141-31-4

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

FLT3-IN-6 is a potent and selective inhibitor of FLT3-ITD (FLT3 mutation) with an IC50 of 1.336 nM[1]. IC50: 1.336 nM (FLT3-ITD)[1]

[1]. Heng H, et al. Combining structure- and property-based optimization to identify selective FLT3-ITD inhibitors with good antitumor efficacy in AML cell inoculated mouse xenograft model. Eur J Med Chem. 2019 Aug 15;176:248-267.

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Average Rating: 5 ★★★★★ (Based on Reviews and 29 reference(s) in Google Scholar.)

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