KAN0438757 |
رقم الكتالوجGC36383 |
KAN0438757 هو مثبط قوي وانتقائي للكيناز الأيضي PFKFB3 مع IC50 من 0.19 ميكرومتر
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Cas No.: 1451255-59-6
Sample solution is provided at 25 µL, 10mM.
KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM [1]. IC50: 0.19 μM (PFKFB3)[1]
[1]. Gustafsson NMS, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018 Sep 24;9(1):3872.
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