Mcl1-IN-11 |
| رقم الكتالوجGC36557 |
Mcl1-IN-11 (المركب G) هو مثبط انتقائي لـ Mcl-1 ، أقل فعالية في Bcl-2 ، مع Kis 0.06 و 4.2 ميكرومتر ، على التوالي
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2042211-13-0
Sample solution is provided at 25 µL, 10mM.
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Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1]. Ki: 0.06 (Mcl-1), 4.2 μM (Bcl-2)[1]
[1]. Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.
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