الصفحة الرئيسية>>Peptides>>Proadrenomedullin (1-20), human

Proadrenomedullin (1-20), human

رقم الكتالوجGC36970

Proadrenomedullin (1-20) ، الإنسان عبارة عن ببتيد مثبط قوي للضغط وإطلاق الكاتيكولامين - الببتيد المثبط الذي يتم إطلاقه من خلايا الكرومافين مع IC50 ~ 350 نانومتر لإفراز الكاتيكولامين في خلايا ورم القواتم PC12 ، ويعمل بطريقة غير تنافسية على وجه التحديد في مستقبلات الكولين النيكوتين [1 ]

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Proadrenomedullin (1-20), human التركيب الكيميائي

Cas No.: 150238-87-2

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Proadrenomedullin (1-20), human is a potent hypotensive and catecholamine release-inhibitory peptide released from chromaffin cells with an IC50 of ~350 nM for catecholamine secretion in PC12 pheochromocytoma cells, acting in a noncompetitive manner specifically at the nicotinic cholinergic receptor[1].

[1]. Mahata M, et al. Proadrenomedullin N-terminal 20 peptide: minimal active region to regulate nicotinic receptors. Hypertension. 1998 Nov;32(5):907-16.

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