Proadrenomedullin (1-20), human |
| Catalog No.GC36970 |
Proadrenomedullin(1-20), 인간은 PC12 갈색세포종 세포에서 카테콜아민 분비에 대해 IC50이 ~350nM인 크로마핀 세포에서 방출되는 강력한 저혈압 및 카테콜아민 방출-억제 펩티드이며, 니코틴성 콜린성 수용체에 비경쟁적 방식으로 작용합니다[1 ].
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 150238-87-2
Sample solution is provided at 25 µL, 10mM.
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Proadrenomedullin (1-20), human is a potent hypotensive and catecholamine release-inhibitory peptide released from chromaffin cells with an IC50 of ~350 nM for catecholamine secretion in PC12 pheochromocytoma cells, acting in a noncompetitive manner specifically at the nicotinic cholinergic receptor[1].
[1]. Mahata M, et al. Proadrenomedullin N-terminal 20 peptide: minimal active region to regulate nicotinic receptors. Hypertension. 1998 Nov;32(5):907-16.
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