RV01 |
رقم الكتالوجGC37576 |
RV01 هو نظير للريسفيراترول ، ويمنع تلف الحمض النووي ، ويقلل من تعبير أسيتالديهيد ديهيدروجينيز 2 (ALDH2) مرنا الناجم عن الإيثانول ، ويعرض نشاط إزالة جذور الهيدروكسيل
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Cas No.: 1016897-10-1
Sample solution is provided at 25 µL, 10mM.
RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity[1]. RV01 decreases iNOS expression, with anti-neuroinflammatory activity[2].
[1]. Yan Y, et al. Protection of resveratrol and its analogues against ethanol-induced oxidative DNA damage in human peripheral lymphocytes. Mutat Res. 2011 Apr 3;721(2):171-7. [2]. Hou Y, et al. A Novel Quinolyl-Substituted Analogue of Resveratrol Inhibits LPS-Induced Inflammatory Responses in Microglial Cells by Blocking the NF-κB/MAPK Signaling Pathways. Mol Nutr Food Res. 2019 Aug 4:e1801380.
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