RV01 |
カタログ番号GC37576 |
RV01 はレスベラ トロールの類似体であり、DNA 損傷を阻害し、エタノールによって誘導されるアセトアルデヒド デヒドロゲナーゼ 2 (ALDH2) mRNA 発現を減少させ、ヒドロキシル ラジカル消去活性を示します 。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1016897-10-1
Sample solution is provided at 25 µL, 10mM.
RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity[1]. RV01 decreases iNOS expression, with anti-neuroinflammatory activity[2].
[1]. Yan Y, et al. Protection of resveratrol and its analogues against ethanol-induced oxidative DNA damage in human peripheral lymphocytes. Mutat Res. 2011 Apr 3;721(2):171-7. [2]. Hou Y, et al. A Novel Quinolyl-Substituted Analogue of Resveratrol Inhibits LPS-Induced Inflammatory Responses in Microglial Cells by Blocking the NF-κB/MAPK Signaling Pathways. Mol Nutr Food Res. 2019 Aug 4:e1801380.
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