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RV01

カタログ番号GC37576

RV01 はレスベラ トロールの類似体であり、DNA 損傷を阻害し、エタノールによって誘導されるアセトアルデヒド デヒドロゲナーゼ 2 (ALDH2) mRNA 発現を減少させ、ヒドロキシル ラジカル消去活性を示します 。

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RV01 化学構造

Cas No.: 1016897-10-1

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity[1]. RV01 decreases iNOS expression, with anti-neuroinflammatory activity[2].

[1]. Yan Y, et al. Protection of resveratrol and its analogues against ethanol-induced oxidative DNA damage in human peripheral lymphocytes. Mutat Res. 2011 Apr 3;721(2):171-7. [2]. Hou Y, et al. A Novel Quinolyl-Substituted Analogue of Resveratrol Inhibits LPS-Induced Inflammatory Responses in Microglial Cells by Blocking the NF-κB/MAPK Signaling Pathways. Mol Nutr Food Res. 2019 Aug 4:e1801380.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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