MALAT1-IN-1 |
رقم الكتالوجGC38711 |
MALAT1-IN-1 (مركبات 5) هو مثبط قوي ومحدد من Malat1 (نسخة 1 من سرطان الغدة الرئوية المرتبط بالورم الخبيث)تعدل MALAT1-IN-1 جينات Malat1 النهائية بطريقة تعتمد على الجرعة دون التأثير على التعبير عن نسخة وفيرة من التخصيب النووي 1 (Neat1)
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Cas No.: 827327-28-6
Sample solution is provided at 25 µL, 10mM.
MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) [1].
[1]. Abulwerdi FA, et al. Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1. ACS Chem Biol. 2019 Feb 15;14(2):223-235.
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