GFB-12811 |
رقم الكتالوجGC64926 |
GFB-12811 هو مثبط CDK5 انتقائي وفعال شفويا مع IC50 من 2.3 نانومتر
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2775311-17-4
Sample solution is provided at 25 µL, 10mM.
GFB-12811 is a high selective and orally active CDK5 inhibitor with an IC50 of 2.3 nM. GFB-12811 is highly selective over the other tested kinases (CDK1/2/6/7/9)[1].
[1]. Daniels MH, et al. Discovery and Optimization of Highly Selective Inhibitors of CDK5. J Med Chem. 2022;65(4):3575-3596.
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Average Rating: 5
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