GlyT1 Inhibitor 1 |
| رقم الكتالوجGC65319 |
مثبط GlyT1 1 هو مثبط قوي وانتقائي لـ GlyT1 مع IC 50 من 38 نانومتر لـ rGlyT1
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1820934-93-7
Sample solution is provided at 25 µL, 10mM.
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GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1[1]. Antipsychotic activity[1].
GlyT1 Inhibitor 1 (Compound 46) demonstrates in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg[1].
[1]. Santora VJ, et al. Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties. J Med Chem. 2018 Jul 26;61(14):6018-6033.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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