GlyT1 Inhibitor 1 |
| Katalog-Nr.GC65319 |
GlyT1 Inhibitor 1 ist ein potenter und selektiver GlyT1-Inhibitor mit einem IC50 von 38 nM fÜr rGlyT1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1820934-93-7
Sample solution is provided at 25 µL, 10mM.
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GlyT1 Inhibitor 1 is a potent and selective GlyT1 inhibitor with an IC50 of 38 nM for rGlyT1[1]. Antipsychotic activity[1].
GlyT1 Inhibitor 1 (Compound 46) demonstrates in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg[1].
[1]. Santora VJ, et al. Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties. J Med Chem. 2018 Jul 26;61(14):6018-6033.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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