GLYX 13 (Synonyms: Rapastinel) |
| رقم الكتالوجGC14121 |
GLYX 13 (GLYX-13) عبارة عن مُعدِّل مستقبلات N-methyl-D-aspartate (NMDAR) التي لها خصائص ناهض جزئي لموقع الجلايسين.
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Cas No.: 117928-94-6
Sample solution is provided at 25 µL, 10mM.
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Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist. Target: NMDARapastinel is a robust cognitive enhancer and facilitates hippocampal long-term potentiation (LTP) of synaptic transmission in slices.
References:
[1]. Burgdorf J, et al. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 2015 Nov 12;308:202-11.
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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