الصفحة الرئيسية>>Signaling Pathways>> Tyrosine Kinase>> ROR>>GNE-0946

GNE-0946

رقم الكتالوجGC31871

GNE-0946 هو ناهض RORγ (RORc) قوي وانتقائي بقيمة EC50 تبلغ 4 نانومتر لخلية HEK-293

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GNE-0946 التركيب الكيميائي

Cas No.: 1677667-24-1

الحجم السعر المخزون الكميّة
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

GNE-0946 is a potent and selective RORγ( RORc) agonist with an EC50 value of 4 nM for HEK-293 cell.

[1]. Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12.

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Average Rating: 5 ★★★★★ (Based on Reviews and 40 reference(s) in Google Scholar.)

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