GNE-0946 |
رقم الكتالوجGC31871 |
GNE-0946 هو ناهض RORγ (RORc) قوي وانتقائي بقيمة EC50 تبلغ 4 نانومتر لخلية HEK-293
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Cas No.: 1677667-24-1
Sample solution is provided at 25 µL, 10mM.
GNE-0946 is a potent and selective RORγ( RORc) agonist with an EC50 value of 4 nM for HEK-293 cell.
[1]. Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12.
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