GSK-F1 |
| رقم الكتالوجGC65309 |
GSK-F1 (المركب F1) هو مثبط PI4KA نشط شفويًا بقيم pIC50 تبلغ 8.0 و 5.9 و 5.8 و 5.9 و 5.9 و 6.4 مقابل PI4KA و PI4KB و PI3KA و PI3KB و PI3KG و PI3KD على التوالي
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1402345-92-9
Sample solution is provided at 25 µL, 10mM.
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GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research[1].
[1]. Bojjireddy N, et al. Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels. J Biol Chem. 2014 Feb 28;289(9):6120-32.
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