HNMPA-(AM)3 |
رقم الكتالوجGC18888 |
HNMPA- (AM) 3 هو مثبط تناظري لمستقبلات الأنسولين التيروزين كيناز ومنفذ للخلايا وانتقائي لمستقبلات الأنسولين التيروزين كيناز
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Cas No.: 120944-03-8
Sample solution is provided at 25 µL, 10mM.
HNMPA-(AM)3 is a cell-permeable prodrug form of the insulin receptor tyrosine kinase (IRTK) inhibitor HNMPA . HNMPA-(AM)3 inhibits IRTK autophosphorylation in CHO cells expressing the human receptor in a concentration- and time-dependent manner. It inhibits 2-deoxyglucose uptake but does not affect insulin-stimulated thymidine uptake in CHO cells at concentrations up to 100 μM.
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