IPR-803 |
| رقم الكتالوجGC39713 |
IPR-803 هو مثبط قوي لتفاعل البروتين والبروتين uPAR • uPA (PPI)يرتبط IPR-803 مباشرة بـ uPAR مع تقارب شبه ميكرو مولارييعرض IPR-803 نشاطًا مضادًا للورم
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Cas No.: 892243-35-5
Sample solution is provided at 25 µL, 10mM.
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IPR-803 is a potent inhibitor of the uPAR•uPA protein-protein interaction (PPI). IPR-803 binds directly to uPAR with sub-micromolar affinity. IPR-803 displays anti-tumor activity[1].
[1]. Mani T, et al. Small-molecule inhibition of the uPAR•uPA interaction: synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis. Bioorg Med Chem. 2013 Apr 1;21(7):2145-55.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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