الصفحة الرئيسية>>Signaling Pathways>> Membrane Transporter/Ion Channel>> ATPase>>Isofalcarintriol

Isofalcarintriol

رقم الكتالوجGC71972 Copy One-Click Copy Product Info

Isofalcarintriol هو منشط NRF2 ومثبط انتقائي من ميتوكوندريا ATP سينثاز.

Products are for research use only. Not for human use. We do not sell to patients.

Isofalcarintriol التركيب الكيميائي

الحجم السعر المخزون الكميّة
1 mg
153٫00
متوفر
5 mg
378٫00
متوفر
10 mg
612٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.



Description of Isofalcarintriol

Isofalcarintriol is a NRF2 activator and selective inhibitor of the mitochondrial ATP synthase. Isofalcarintriol can be used for aging study.

References:
[1]. Thomas C, et al. A naturally occurring polyacetylene isolated from carrots promotes health and delays signatures of aging. Nat Commun. 2023;14(1):8142. Published 2023 Dec 8.

Chemical Properties of Isofalcarintriol

Cas No. SDF
Formula C17H26O3 M.Wt 278.39
الذوبان Storage
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Isofalcarintriol

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.5921 mL 17.9604 mL 35.9208 mL
5 mM 718.4 μL 3.5921 mL 7.1842 mL
10 mM 359.2 μL 1.796 mL 3.5921 mL
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In vivo Formulation Calculator (Clear solution) of Isofalcarintriol

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Isofalcarintriol

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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