Isofraxidin |
| رقم الكتالوجGC39134 |
Isofraxidin ، أحد مكونات الكومارين من Acanthopanax senticosus ، يمنع التعبير MMP-7 وغزو الخلايا لخلايا الورم الكبدي البشري
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 486-21-5
Sample solution is provided at 25 µL, 10mM.
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Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2].
[1]. Yamazaki T, et al. Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits matrix metalloproteinase-7 expression and cell invasion of human hepatoma cells.Biol Pharm Bull. 2010;33(10):1716-22. [2]. Jin J , et al. Isofraxidin targets the TLR4/MD-2 axis to prevent osteoarthritis development.Food Funct. 2018 Nov 14;9(11):5641-5652.
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