LSD1/HDAC6-IN-1 |
| رقم الكتالوجGC62434 |
LSD1 / HDAC6-IN-1 هو مثبط مزدوج نشط عن طريق الفم من مادة لايسين محددة لديميثيلاز 1 (LSD1) / هيستون ديسيتيلاز 6 (HDAC6) ، مع نشاط مضاد للورميمكن استخدام LSD1 / HDAC6-IN-1 للبحث عن المايلوما المتعددة (MM)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2738306-38-0
Sample solution is provided at 25 µL, 10mM.
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LSD1/HDAC6-IN-1 is an orally active dual inhibitor of lysine specific demethylase 1(LSD1)/Histone deacetylase 6 (HDAC6), with anti-tumor activity. LSD1/HDAC6-IN-1 can be used for the research of multiple myeloma (MM)[1].
LSD1/HDAC6-IN-1 shows superior potency in multiple MM lines[1].
LSD1/HDAC6-IN-1 is efficacy in the MM.1S xenograft model[1].
[1]. M Naveen Sadhu, et al. Novel dual LSD1/HDAC6 inhibitors for the treatment of multiple myeloma. Bioorg Med Chem Lett. 2020 Dec 24;34:127763.
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